DPPA5P4

Across TCGA patient cohorts, DPPA5P4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,299 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DPPA5P4-associated genes across cancer lineages are SYPL1, FIS1, and AGAP2. Each is linked with DPPA5P4 in more than 7 cancer types. Because this analysis shows association rather than direction, both DPPA5P4-to-partner and partner-to-DPPA5P4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPPA5P4 versus SYPL1 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA5P4→partner) and Y-score (partner→DPPA5P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SYPL1 →	+0.785	+0.459	<.001	<.001	3	8
HNSC	FIS1 →	+0.810	+0.273	<.001	.004	3	5
GBM	AGAP2 →	-1.082	-0.374	.005	<.001	3	5
LSCC	HSPB1 →	+1.124	+0.467	<.001	.001	3	4
HNSC	ZNHIT1 →	+0.802	+0.436	<.001	<.001	3	4
HNSC	TRPV4 →	+0.938	+0.297	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,299 associations by consensus.

DPPA5P4 vs SYPL1 — LSCC

Explore this scatter interactively →