Across TCGA patient cohorts, DPPA3 mutation is significantly associated with the RNA expression of many other genes, with 1,175 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPPA3-associated genes across cancer lineages are VN1R6P, ARSFP1, and MYO19. Each is linked with DPPA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPPA3-to-partner and partner-to-DPPA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA3→partner) and Y-score (partner→DPPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VN1R6P →	+0.047	+5.038	.008	.009	3	2
COAD	ARSFP1 →	+0.372	+4.151	<.001	.004	3	2
SKCM	MYO19 →	+0.494	+3.710	<.001	<.001	3	2
SKCM	KRT8P4 →	+0.177	+1.874	<.001	.003	3	2
SKCM	PHF5A →	+0.359	+3.509	.009	.002	3	2
SKCM	CCM2L →	-0.378	-2.081	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,175 associations by consensus.

Exploration

DPPA3 survival (RNA) · tumor vs normal (RNA) · all DPPA3 data types