Q-omics provides the consensus-scored KRT8P4 profile across patient tissues and cancer cell-line models. KRT8P4 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, KRT8P4 is differentially expressed in 6, with the highest sampling consensus in LUSC. Additionally, KRT8P4 RNA expression shows 7,417 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KICH, LUSC, and GBM as cancer lineages where KRT8P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KRT8P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KRT8P4 survival associations across molecular data types. KRT8P4 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KRT8P4 RNA expression–survival associations across cancer types. High KRT8P4 expression shows unfavorable associations in KICH, COAD, UVM, SKCM, READ and KIRC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for KRT8P4 RNA expression.
This table summarizes KRT8P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for KRT8P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KRT8P4 shows lower tumor expression in STAD and higher tumor expression in LUSC, BRCA, KIRP, KIRC and READ. The LUSC box plot shows higher KRT8P4 RNA expression in tumor versus normal tissue (log2 FC = +0.030, t-test p = .001).
This table shows molecular features associated with KRT8P4 in patient tissues and cancer cell lines. In patient samples, KRT8P4 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
