DPH6-DT

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPH6-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,144 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DPH6-DT-associated GO terms across cancer lineages are Intraciliary transport, Positive regulation of translation in response to stress, and Regulation of lysosome organization. Each is linked with DPH6-DT in more than 20 cancer types. Because this analysis shows association rather than direction, both DPH6-DT-to-partner and partner-to-DPH6-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by DPH6-DT-low versus DPH6-DT-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH6-DT→partner) and Y-score (partner→DPH6-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAIntraciliary transport →+0.052+0.209<.001<.001321
THYMPositive regulation of translation in response to stress →+0.067+0.542<.001<.001320
THYMRegulation of lysosome organization →+0.053+0.555<.001<.001320
TGCTDorsal/ventral neural tube patterning →+0.056+0.258<.001<.001319
LAMLProtein localization to ciliary membrane →+0.062+0.212<.001<.001220
ESCANegative regulation of telomere capping →+0.055+0.230<.001<.001220
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,144 associations by consensus.

Intraciliary transport by DPH6-DT expression — ESCA

Box plot of Intraciliary transport in DPH6-DT-low vs DPH6-DT-high samples in ESCA.

Explore this box plot interactively →

Exploration