DPH6-DT

Across TCGA pan-cancer cohorts, DPH6-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DPH6-DT data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DPH6-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DPH6-DT expression acts as an unfavorable survival marker, although some lineages such as ACC and KIRC show a favorable association.

ACC, KIRC, and KIRP are the cancer types where DPH6-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.732	0.436	<.001	111	view →
KIRC	OS	Tertile	All	0.728	0.526	<.001	72	view →
KIRP	DFS	Median	All	0.967	0.569	<.001	60	view →
PAAD	DFS	Median	All	0.392	0.192	<.001	46	view →
THCA	OS	Tertile	All	0.975	0.995	.005	44	view →
BRCA	DFS	Tertile	IV	0.371	0.985	.001	36	view →
CESC	OS	Median	II,III,IV	0.749	0.891	.007	36	view →
KICH	DFS	Tertile	All	0.622	1.000	.001	31	view →
GBM	OS	Median	All	0.241	0.571	<.001	24	view →
LUSC	DFS	Tertile	All	0.622	0.376	.008	21	view →
SKCM	OS	Quartile	All	0.407	0.224	<.001	18	view →
LGG	OS	Quartile	All	0.785	0.920	.004	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DPH6-DT–ACC (DFS)

Open the ACC breakdown →