DOLK

Across TCGA cell cohorts, DOLK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,071 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DOLK-associated GO terms across cancer lineages are Dolichyl monophosphate biosynthetic process, Protein deneddylation, and Positive regulation of RNA splicing. Each is linked with DOLK in more than 18 cancer types. Because this analysis shows association rather than direction, both DOLK-to-partner and partner-to-DOLK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dolichyl monophosphate biosynthetic process grouped by DOLK-low versus DOLK-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOLK→partner) and Y-score (partner→DOLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Dolichyl monophosphate biosynthetic process →	+0.149	+0.945	<.001	<.001	3	19
BREAST	Protein deneddylation →	+0.116	+0.664	<.001	.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of RNA splicing →	+0.104	+0.803	<.001	<.001	3	13
BLOOD_Lymphoma	mRNA export from nucleus →	+0.086	+0.871	<.001	<.001	3	13
STOMACH	Response to oscillatory fluid shear stress →	+0.138	+0.657	.001	.001	3	13
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.138	+0.657	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,071 associations by consensus.

Dolichyl monophosphate biosynthetic process by DOLK expression — BREAST

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