DNM3-IT1

Across TCGA patient cohorts, DNM3-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,686 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNM3-IT1-associated proteins across cancer lineages are BRD4, PABPN1, and MYEF2. Each is linked with DNM3-IT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNM3-IT1-to-partner and partner-to-DNM3-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNM3-IT1 versus BRD4 in HNSC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3-IT1→partner) and Y-score (partner→DNM3-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BRD4 →	+0.169	+0.468	.003	<.001	3	4
PDAC	PABPN1 →	+0.857	+0.441	.002	<.001	3	4
LSCC	MYEF2 →	+0.639	+0.498	<.001	<.001	3	4
LSCC	U2SURP_S202 →	+0.779	+0.676	.004	.002	3	3
BRCA	MYLK →	+0.410	+0.240	<.001	.002	3	3
GBM	ARFGEF3 →	+0.450	+0.966	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,686 associations by consensus.

DNM3-IT1 vs BRD4 — HNSC

Explore this scatter interactively →