DNAJC4

Across TCGA patient cohorts, DNAJC4 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC4-associated genes across cancer lineages are MIR6747, RN7SL575P, and RNU6-1312P. Each is linked with DNAJC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC4-to-partner and partner-to-DNAJC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6747 grouped by DNAJC4-low versus DNAJC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC4→partner) and Y-score (partner→DNAJC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6747 →	+1.661	+3.942	<.001	.004	3	1
UCEC	RN7SL575P →	+0.261	+3.764	.008	.003	3	1
LUSC	RNU6-1312P →	+0.261	+7.924	<.001	.008	3	1
LUSC	RNU6-508P →	+0.269	+7.924	.001	.008	3	1
LUSC	RNU4-17P →	+0.208	+7.924	<.001	.008	3	1
LUSC	MIR329-1 →	+0.205	+7.924	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

MIR6747 by DNAJC4 expression — UCEC

Explore this box plot interactively →