DNAJC28

Across TCGA patient cohorts, DNAJC28 mutation is significantly associated with the RNA expression of many other genes, with 2,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC28-associated genes across cancer lineages are OSBPL9P5, RNU6-1069P, and MIR6803. Each is linked with DNAJC28 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC28-to-partner and partner-to-DNAJC28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OSBPL9P5 grouped by DNAJC28-low versus DNAJC28-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC28→partner) and Y-score (partner→DNAJC28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OSBPL9P5 →	+0.156	+6.040	<.001	.001	3	2
UCEC	RNU6-1069P →	+0.686	+1.574	<.001	.009	3	2
UCEC	MIR6803 →	+0.090	+4.019	<.001	.005	3	2
HNSC	RNU4-88P →	+0.653	+7.954	<.001	.008	3	2
BLCA	MTHFD2P3 →	+0.150	+5.444	<.001	.002	3	2
BLCA	LINC02123 →	+0.050	+5.618	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,659 associations by consensus.

OSBPL9P5 by DNAJC28 expression — BLCA

Explore this box plot interactively →