DNAJC28

Across TCGA pan-cancer cohorts, DNAJC28 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated DNAJC28 data layer compared with 4 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNAJC28 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DNAJC28 expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRP show a favorable association.

LUAD, KIRP, and UVM are the cancer types where DNAJC28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.417	0.140	<.001	76	view →
KIRP	OS	Tertile	All	0.892	0.583	<.001	68	view →
UVM	OS	Median	III,IV	0.388	0.908	.001	51	view →
KIRC	OS	Tertile	All	0.751	0.541	<.001	45	view →
COAD	OS	Tertile	All	0.934	0.833	.004	45	view →
PAAD	DFS	Quartile	All	0.473	0.243	<.001	42	view →
LGG	DFS	Quartile	All	0.629	0.815	<.001	34	view →
MESO	DFS	Median	II,III,IV	0.203	0.698	<.001	27	view →
ESCA	OS	Median	II,III,IV	0.647	0.342	<.001	25	view →
OV	OS	Quartile	IV	0.765	0.521	.015	20	view →
BRCA	OS	Tertile	All	0.973	0.947	.007	20	view →
SCLC	DFS	Median	IV	0.137	0.559	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

DNAJC28–LUAD (OS)

Open the LUAD breakdown →