DNAJC11

Across TCGA patient cohorts, DNAJC11 mutation is significantly associated with the RNA expression of many other genes, with 3,278 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC11-associated genes across cancer lineages are KIR2DL4, LINC01943, and SFPQP1. Each is linked with DNAJC11 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNAJC11-to-partner and partner-to-DNAJC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DL4 grouped by DNAJC11-low versus DNAJC11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC11→partner) and Y-score (partner→DNAJC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIR2DL4 →	+0.397	+1.686	.003	.001	3	3
UCEC	LINC01943 →	+0.359	+1.676	.001	.001	3	2
CESC	SFPQP1 →	+0.021	+4.342	<.001	.007	3	2
CESC	PSAT1P4 →	+0.085	+3.918	<.001	.001	3	2
UCEC	CIRBP-AS1 →	+0.528	+3.279	<.001	<.001	3	2
CESC	LINC02438 →	+1.346	+3.726	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,278 associations by consensus.

KIR2DL4 by DNAJC11 expression — UCEC

Explore this box plot interactively →