DNAJC11

Across TCGA pan-cancer cohorts, DNAJC11 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of DNAJC11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where DNAJC11 RNA is repressed in tumor relative to normal tissue. In most cancer types DNAJC11 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and KIRP are the cancer types where DNAJC11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DNAJC11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.726	<.001	10	view →
KIRC	Male	II,III,IV	−1.255	<.001	10	view →
KIRP	Male	All	−1.247	<.001	9	view →
BLCA	Female	All	+0.665	<.001	9	view →
THCA	All	II,III,IV	−0.626	<.001	9	view →
LUAD	Male	All	+0.413	<.001	8	view →
LUSC	Male	II,III,IV	+0.736	<.001	7	view →
STAD	Male	II,III,IV	+1.102	<.001	6	view →
CHOL	All	All	+0.774	.006	4	view →
HNSC	All	All	+0.406	.003	4	view →
LIHC	Female	III,IV	+0.637	.016	2	view →
COAD	Female	IV	−0.550	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

DNAJC11–KICH

Open the KICH breakdown →