DNAJA3

Across TCGA patient cohorts, DNAJA3 mutation is significantly associated with the RNA expression of many other genes, with 2,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJA3-associated genes across cancer lineages are RN7SL248P, RNA5SP413, and OSBPL9P3. Each is linked with DNAJA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJA3-to-partner and partner-to-DNAJA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by DNAJA3-low versus DNAJA3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJA3→partner) and Y-score (partner→DNAJA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL248P →	+0.212	+7.584	<.001	<.001	3	2
LUSC	RNA5SP413 →	+1.750	+6.081	<.001	.002	3	2
LUSC	OSBPL9P3 →	+0.086	+5.474	.004	.005	3	2
BRCA	MTND1P35 →	+0.059	+7.731	<.001	.009	3	2
UCEC	RNA5SP419 →	+0.718	+2.340	<.001	<.001	3	2
UCEC	RNA5SP416 →	+0.475	+1.944	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,048 associations by consensus.

RN7SL248P by DNAJA3 expression — CESC

Explore this box plot interactively →