DNAH11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAH11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,235 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAH11-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Cellular detoxification, and Regulation of cell cycle G1/S phase transition. Each is linked with DNAH11 in more than 11 cancer types. Because this analysis shows association rather than direction, both DNAH11-to-partner and partner-to-DNAH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to mitochondrion grouped by DNAH11-low versus DNAH11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH11→partner) and Y-score (partner→DNAH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of protein localization to mitochondrion →+0.124+1.245<.001.001312
BONECellular detoxification →-0.092-1.725<.001.00139
BLOOD_LeukemiaRegulation of cell cycle G1/S phase transition →+0.060+0.429<.001<.00139
STOMACHDNA-templated transcription initiation →+0.078+0.921<.001<.00138
LIVERPositive regulation of autophagy →+0.043+1.111.002.00838
LIVERPositive regulation of protein localization to plasma membrane →+0.114+1.147.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,235 associations by consensus.

Regulation of protein localization to mitochondrion by DNAH11 expression — STOMACH

Box plot of Regulation of protein localization to mitochondrion in DNAH11-low vs DNAH11-high samples in STOMACH.

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