DNAH11

Across TCGA cell cohorts, DNAH11 mutation is significantly associated with the RNA expression of many other genes, with 1,895 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAH11-associated genes across cancer lineages are CNDP2, C1QBP, and PDS5A. Each is linked with DNAH11 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAH11-to-partner and partner-to-DNAH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNDP2 grouped by DNAH11-low versus DNAH11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAH11→partner) and Y-score (partner→DNAH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CNDP2 →	-0.591	-3.169	.008	.008	3	4
LARGE_INTESTINE	C1QBP →	+0.759	+3.003	<.001	<.001	3	4
LARGE_INTESTINE	PDS5A →	+0.547	+1.706	<.001	<.001	3	4
LARGE_INTESTINE	CSNK1G1 →	+0.459	+1.706	.001	<.001	3	4
LARGE_INTESTINE	COX10 →	+0.649	+2.700	<.001	<.001	3	4
BLOOD_Myeloma	C11orf65 →	+0.446	+3.169	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,895 associations by consensus.

CNDP2 by DNAH11 expression — BLOOD_Lymphoma

Explore this box plot interactively →