DMXL1

Across TCGA patient cohorts, DMXL1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,898 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DMXL1-associated genes across cancer lineages are PIK3R5, WDR35, and MEX3A. Each is linked with DMXL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DMXL1-to-partner and partner-to-DMXL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMXL1 versus PIK3R5 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMXL1→partner) and Y-score (partner→DMXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIK3R5 →	+0.675	+0.157	<.001	<.001	3	6
LSCC	WDR35 →	-0.534	-0.157	<.001	<.001	3	6
BRCA	MEX3A →	-0.997	-0.210	<.001	<.001	3	6
OV	MAN1A1 →	+1.108	+0.285	.002	<.001	3	5
HNSC	ELL2 →	+0.891	+0.179	<.001	<.001	3	5
COAD	CSF3R →	+0.956	+0.298	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,898 associations by consensus.

DMXL1 vs PIK3R5 — LSCC

Explore this scatter interactively →