DMTF1

Across TCGA patient cohorts, DMTF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,442 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMTF1-associated proteins across cancer lineages are GTF2I, BIN2_S444, and CKAP4_S26. Each is linked with DMTF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DMTF1-to-partner and partner-to-DMTF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMTF1 versus GTF2I in GBM, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMTF1→partner) and Y-score (partner→DMTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF2I →	+0.427	+0.473	<.001	<.001	3	6
BRCA	BIN2_S444 →	-1.090	-0.589	<.001	.006	3	5
LUAD	CKAP4_S26 →	-0.801	-0.426	<.001	<.001	3	5
LSCC	CUX1_S1069 →	+0.500	+0.253	<.001	<.001	3	5
GBM	DEK →	+0.282	+0.336	.003	<.001	3	5
LSCC	EVI2B →	-0.577	-0.381	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,442 associations by consensus.

DMTF1 vs GTF2I — GBM

Explore this scatter interactively →