DMTF1

Across TCGA patient cohorts, DMTF1 mutation is significantly associated with the RNA expression of many other genes, with 2,959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DMTF1-associated genes across cancer lineages are RNU6-264P, TMEM225, and ANKRD33B-AS1. Each is linked with DMTF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DMTF1-to-partner and partner-to-DMTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-264P grouped by DMTF1-low versus DMTF1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMTF1→partner) and Y-score (partner→DMTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-264P →	+0.212	+4.342	<.001	.007	3	3
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	2
READ	ANKRD33B-AS1 →	+0.187	+6.681	<.001	<.001	3	2
SKCM	MATR3P1 →	+0.111	+3.449	<.001	.002	3	2
CESC	CCDC169-SOHLH2 →	+0.088	+4.125	<.001	.002	3	2
CESC	SPDYE22P →	+0.084	+3.859	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,959 associations by consensus.

RNU6-264P by DMTF1 expression — CESC

Explore this box plot interactively →