DMTF1

Across TCGA cell cohorts, DMTF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,100 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DMTF1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Microtubule nucleation, and Regulation of RNA splicing. Each is linked with DMTF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both DMTF1-to-partner and partner-to-DMTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by DMTF1-low versus DMTF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMTF1→partner) and Y-score (partner→DMTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.208	+1.130	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Microtubule nucleation →	+0.118	+1.319	<.001	<.001	3	18
LARGE_INTESTINE	Regulation of RNA splicing →	+0.088	+1.061	<.001	<.001	3	17
BONE	Microtubule polymerization →	+0.143	+1.257	<.001	<.001	3	17
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.107	+1.069	<.001	<.001	3	17
LARGE_INTESTINE	RNA localization →	+0.085	+0.988	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,100 associations by consensus.

Pre-mRNA catabolic process by DMTF1 expression — BONE

Explore this box plot interactively →