DMRTB1

Across TCGA patient cohorts, DMRTB1 mutation is significantly associated with the RNA expression of many other genes, with 1,038 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DMRTB1-associated genes across cancer lineages are RNU6-1216P, RN7SKP230, and MIR450A2. Each is linked with DMRTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRTB1-to-partner and partner-to-DMRTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1216P grouped by DMRTB1-low versus DMRTB1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTB1→partner) and Y-score (partner→DMRTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1216P →	+0.570	+4.707	<.001	<.001	3	2
COAD	RN7SKP230 →	+0.653	+3.759	<.001	.004	3	2
READ	MIR450A2 →	+0.566	+5.257	<.001	.002	3	2
READ	NDUFB4P4 →	+0.424	+4.925	<.001	.004	3	2
READ	EIF3JP1 →	+0.453	+4.626	<.001	.004	3	2
READ	OR8B9P →	+0.070	+4.925	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,038 associations by consensus.

RNU6-1216P by DMRTB1 expression — COAD

Explore this box plot interactively →