DMC1

Across TCGA patient cohorts, DMC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,872 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DMC1-associated proteins across cancer lineages are MCM6, RFC4, and MCM2. Each is linked with DMC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DMC1-to-partner and partner-to-DMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMC1 versus MCM6 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMC1→partner) and Y-score (partner→DMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM6 →	+0.707	+0.420	<.001	<.001	3	8
LSCC	RFC4 →	+0.369	+0.752	.005	<.001	3	7
LUAD	MCM2 →	+0.692	+0.438	<.001	<.001	3	7
OV	MCM2_S139 →	+0.771	+0.801	<.001	<.001	3	7
OV	MCM3 →	+0.651	+0.830	.001	.001	3	7
LUAD	MCM4 →	+0.715	+0.452	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,872 associations by consensus.

DMC1 vs MCM6 — LUAD

Explore this scatter interactively →