DM1-AS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DM1-AS RNA expression is significantly associated with the protein abundance of many other proteins, with 10,166 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DM1-AS-associated proteins across cancer lineages are VEZF1, IRF2BP1, and JPT1. Each is linked with DM1-AS in more than 4 cancer types. Because this analysis shows association rather than direction, both DM1-AS-to-partner and partner-to-DM1-AS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DM1-AS versus VEZF1 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DM1-AS→partner) and Y-score (partner→DM1-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAVEZF1 →+0.385+0.641<.001<.00135
HNSCIRF2BP1 →+0.360+0.497<.001<.00135
BRCAJPT1 →-0.548-0.798<.001<.00134
GBMHNRNPUL1 →+0.371+0.513<.001<.00134
LSCCUBA2 →+0.302+0.449<.001<.00134
GBMDHX9 →+0.216+0.427<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,166 associations by consensus.

DM1-AS vs VEZF1 — BRCA

Per-sample scatter of DM1-AS vs VEZF1 in BRCA (Pearson r = 0.36).

Explore this scatter interactively →

Exploration