DLK2

Across TCGA patient cohorts, DLK2 protein abundance is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLK2-associated genes across cancer lineages are C10orf95, DNAJB5, and ATG10. Each is linked with DLK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLK2-to-partner and partner-to-DLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLK2 versus C10orf95 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK2→partner) and Y-score (partner→DLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C10orf95 →	+0.102	+0.796	.005	.003	3	1
LSCC	DNAJB5 →	-0.736	-0.809	.002	.008	3	1
LSCC	ATG10 →	+0.470	+0.690	.007	.006	3	1
LSCC	ATF3 →	-1.421	-0.878	<.001	.005	3	1
LSCC	LINC01555 →	-0.051	-0.795	.004	.005	3	1
LSCC	CSMD1 →	+1.584	+1.114	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

DLK2 vs C10orf95 — LSCC

Explore this scatter interactively →