DLGAP4

Across TCGA patient cohorts, DLGAP4 mutation is significantly associated with the RNA expression of many other genes, with 5,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLGAP4-associated genes across cancer lineages are FANCB, SKA1, and MIS18A. Each is linked with DLGAP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DLGAP4-to-partner and partner-to-DLGAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FANCB grouped by DLGAP4-low versus DLGAP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP4→partner) and Y-score (partner→DLGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FANCB →	+0.284	+1.637	.002	.001	3	5
COAD	SKA1 →	+0.726	+3.598	<.001	.001	3	4
LUAD	MIS18A →	+0.666	+3.482	.001	.002	2	5
COAD	C18orf54 →	+0.607	+3.625	<.001	.001	3	4
STAD	ESCO2 →	+0.738	+3.459	<.001	.004	3	4
UCEC	RRM2 →	+0.724	+1.825	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,359 associations by consensus.

FANCB by DLGAP4 expression — UCEC

Explore this box plot interactively →