DLD

Across TCGA patient cohorts, DLD RNA expression is significantly associated with the protein abundance of many other proteins, with 12,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLD-associated proteins across cancer lineages are PUS7, PEX1, and TNPO3. Each is linked with DLD in more than 7 cancer types. Because this analysis shows association rather than direction, both DLD-to-partner and partner-to-DLD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLD versus PUS7 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLD→partner) and Y-score (partner→DLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PUS7 →	+0.617	+0.556	<.001	<.001	3	8
UCEC	PEX1 →	+0.343	+0.348	.002	.001	3	7
LUAD	TNPO3 →	+0.308	+0.493	<.001	<.001	3	6
COAD	CLUH →	+0.382	+0.453	<.001	<.001	3	6
HNSC	DNAJC2 →	+0.408	+1.079	<.001	<.001	3	6
BRCA	EIF4H →	+0.237	+0.632	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,933 associations by consensus.

DLD vs PUS7 — BRCA

Explore this scatter interactively →