DIRC3-AS1

Across TCGA patient cohorts, DIRC3-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,593 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DIRC3-AS1-associated proteins across cancer lineages are IGFBP5, IGFBP5_S116, and ISLR. Each is linked with DIRC3-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DIRC3-AS1-to-partner and partner-to-DIRC3-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIRC3-AS1 versus IGFBP5 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DIRC3-AS1→partner) and Y-score (partner→DIRC3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IGFBP5 →	+0.809	+0.721	<.001	<.001	3	7
BRCA	IGFBP5_S116 →	+0.819	+0.157	<.001	.003	3	7
HNSC	ISLR →	+0.616	+0.573	<.001	<.001	3	6
BRCA	P4HA1 →	+0.592	+0.222	.002	.004	3	5
HNSC	PCOLCE →	+0.721	+0.739	<.001	<.001	3	5
OV	THBS3 →	+0.665	+0.183	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,593 associations by consensus.

DIRC3-AS1 vs IGFBP5 — LSCC

Explore this scatter interactively →