DIPK2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DIPK2B mutation is significantly associated with the RNA expression of many other genes, with 3,570 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DIPK2B-associated genes across cancer lineages are MIR2276, PRAMEF35P, and RNA5SP319. Each is linked with DIPK2B in more than 2 cancer types. Because this analysis shows association rather than direction, both DIPK2B-to-partner and partner-to-DIPK2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR2276 grouped by DIPK2B-low versus DIPK2B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2B→partner) and Y-score (partner→DIPK2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR2276 →+0.442+5.588<.001.00433
LIHCPRAMEF35P →+0.043+4.758<.001.00633
SKCMRNA5SP319 →+0.133+2.775<.001.00433
SARCFAM96AP1 →+0.113+5.111<.001.00832
LUSCPTGES3P5 →+0.435+4.978<.001<.00132
BLCASDHDP4 →+0.138+5.329<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

MIR2276 by DIPK2B expression — BLCA

Box plot of MIR2276 in DIPK2B-low vs DIPK2B-high samples in BLCA.

Explore this box plot interactively →

Exploration