PRAMEF35P

Q-omics provides the consensus-scored PRAMEF35P profile across patient tissues and cancer cell-line models. PRAMEF35P expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, PRAMEF35P RNA expression shows 6,221 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCEC, and STAD as cancer lineages where PRAMEF35P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PRAMEF35P survival associations across molecular data types. PRAMEF35P RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PRAMEF35P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	UCEC (66)	view →

This table ranks reproducible PRAMEF35P RNA expression–survival associations across cancer types. High PRAMEF35P expression shows unfavorable associations in UCEC, BRCA, DLBC, ESCA and TGCT, but favorable associations in STAD. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UCEC as the clearest survival context for PRAMEF35P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.448	0.661	.001	66	view →
BRCA	OS	Tertile	II,III,IV	0.136	0.566	.008	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
STAD	OS	Tertile	IV	0.805	0.266	.040	27	view →
ESCA	DFS	Tertile	All	0.148	0.673	.040	18	view →
TGCT	DFS	Tertile	All	0.066	0.802	<.001	18	view →

Pink = unfavorable, green = favorable. all 10 lineages →

PRAMEF35P-UCEC (DFS)

Explore this curve interactively →