DIO2-AS1

Across TCGA patient cohorts, DIO2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,192 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DIO2-AS1-associated proteins across cancer lineages are SP4_S46, MYLK_S1759, and MYOF. Each is linked with DIO2-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DIO2-AS1-to-partner and partner-to-DIO2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIO2-AS1 versus SP4_S46 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DIO2-AS1→partner) and Y-score (partner→DIO2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SP4_S46 →	+0.759	+0.628	<.001	<.001	3	4
PDAC	MYLK_S1759 →	+1.031	+0.185	.001	<.001	3	3
LUAD	MYOF →	-0.473	-0.424	<.001	<.001	3	3
HNSC	NADSYN1 →	-0.421	-0.484	<.001	.001	3	3
HNSC	NFATC2_S363 →	+0.849	+0.630	.007	.001	3	3
HNSC	PLD1 →	-0.408	-0.635	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,192 associations by consensus.

DIO2-AS1 vs SP4_S46 — GBM

Explore this scatter interactively →