DHX33-DT

Across TCGA patient cohorts, DHX33-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 4,481 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DHX33-DT-associated proteins across cancer lineages are CAST_S499, AKAP13_S2498, and ALKBH5_S384. Each is linked with DHX33-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both DHX33-DT-to-partner and partner-to-DHX33-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX33-DT versus CAST_S499 in HNSC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX33-DT→partner) and Y-score (partner→DHX33-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CAST_S499 →	-0.555	-0.472	.003	.007	2	4
CCRCC	AKAP13_S2498 →	-0.511	-0.197	.008	.003	3	3
CCRCC	ALKBH5_S384 →	+0.848	+0.637	.008	.001	3	3
OV	LAMTOR1_S63 →	-0.616	-0.136	.004	.002	3	3
CCRCC	EIF4EBP2_T70 →	+1.127	+0.523	<.001	.001	3	3
LUAD	AKT1S1_T246 →	+0.605	+0.153	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,481 associations by consensus.

DHX33-DT vs CAST_S499 — HNSC

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