DHX33-DT

Across TCGA pan-cancer cohorts, DHX33-DT RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DHX33-DT data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher DHX33-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated DHX33-DT expression acts as an unfavorable survival marker, although some lineages such as OV and PAAD show a favorable association.

OV, LGG, and DLBC are the cancer types where DHX33-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	All	0.791	0.647	<.001	66	view →
LGG	DFS	Tertile	All	0.611	0.773	<.001	48	view →
DLBC	DFS	Quartile	III,IV	0.079	0.787	.001	41	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
PAAD	OS	Tertile	All	0.729	0.269	.004	33	view →
HNSC	DFS	Tertile	IV	1.000	0.521	.014	33	view →
LUAD	DFS	Tertile	III,IV	0.252	0.532	.039	27	view →
ACC	DFS	Tertile	III,IV	0.326	0.461	.039	24	view →
KIRP	OS	Tertile	III,IV	0.805	0.388	.024	20	view →
COAD	DFS	Tertile	All	0.246	0.560	.005	15	view →
KIRC	OS	Tertile	II,III,IV	0.406	0.549	.038	12	view →
THYM	OS	Median	All	0.959	0.759	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DHX33-DT–OV (OS)

Open the OV breakdown →