DHRS7

Across TCGA patient cohorts, DHRS7 protein abundance is significantly associated with the RNA expression of many other genes, with 13,701 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHRS7-associated genes across cancer lineages are ECT2, SMC3, and ARHGDIB. Each is linked with DHRS7 in more than 4 cancer types. Because this analysis shows association rather than direction, both DHRS7-to-partner and partner-to-DHRS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHRS7 versus ECT2 in LSCC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7→partner) and Y-score (partner→DHRS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ECT2 →	-0.844	-0.350	<.001	<.001	3	5
UCEC	SMC3 →	-0.643	-0.609	<.001	<.001	3	4
OV	ARHGDIB →	+1.104	+0.475	<.001	<.001	3	4
LSCC	STAG1 →	-0.519	-0.443	<.001	<.001	3	4
LUAD	NPC2 →	+0.994	+0.504	<.001	<.001	3	4
UCEC	SNRPF →	-0.898	-0.602	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,701 associations by consensus.

DHRS7 vs ECT2 — LSCC

Explore this scatter interactively →