DHRS7

Across TCGA cell cohorts, DHRS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,729 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DHRS7-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Endosome to lysosome transport. Each is linked with DHRS7 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHRS7-to-partner and partner-to-DHRS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by DHRS7-low versus DHRS7-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7→partner) and Y-score (partner→DHRS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein catabolic process at synapse →	+0.137	+1.376	<.001	<.001	3	9
PANCREAS	Protein catabolic process at postsynapse →	+0.137	+1.376	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Endosome to lysosome transport →	+0.070	+0.630	<.001	.001	3	9
SOFT_TISSUE	Response to endoplasmic reticulum stress →	+0.039	+0.837	.006	.006	3	9
SKIN	Microtubule depolymerization →	-0.080	-0.530	<.001	.005	3	9
BONE	Regulation of double-strand break repair →	-0.070	-1.604	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,729 associations by consensus.

Protein catabolic process at synapse by DHRS7 expression — PANCREAS

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