DHRS11

Across TCGA cell cohorts, DHRS11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,687 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DHRS11-associated GO terms across cancer lineages are Estrogen biosynthetic process, Angiogenesis, and DNA strand elongation involved in DNA replication. Each is linked with DHRS11 in more than 13 cancer types. Because this analysis shows association rather than direction, both DHRS11-to-partner and partner-to-DHRS11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Estrogen biosynthetic process grouped by DHRS11-low versus DHRS11-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS11→partner) and Y-score (partner→DHRS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Estrogen biosynthetic process →	+0.250	+1.373	<.001	.001	3	14
SOFT_TISSUE	Angiogenesis →	-0.074	-0.841	<.001	<.001	3	9
PANCREAS	DNA strand elongation involved in DNA replication →	+0.138	+0.651	<.001	.004	3	9
SOFT_TISSUE	DNA replication checkpoint signaling →	+0.160	+0.903	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.158	+0.618	<.001	.003	3	9
CNS	Extracellular matrix organization →	-0.122	-0.770	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Estrogen biosynthetic process by DHRS11 expression — LIVER

Explore this box plot interactively →