DHCR24

Across TCGA cell cohorts, DHCR24 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,551 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHCR24-associated GO terms across cancer lineages are Zymosterol metabolic process, Zymosterol biosynthetic process, and Sterol biosynthetic process. Each is linked with DHCR24 in more than 19 cancer types. Because this analysis shows association rather than direction, both DHCR24-to-partner and partner-to-DHCR24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zymosterol metabolic process grouped by DHCR24-low versus DHCR24-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHCR24→partner) and Y-score (partner→DHCR24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Zymosterol metabolic process →	+0.261	+1.111	<.001	<.001	3	20
BONE	Zymosterol biosynthetic process →	+0.261	+1.111	<.001	<.001	3	20
BONE	Sterol biosynthetic process →	+0.194	+0.919	<.001	<.001	3	19
BONE	Secondary alcohol biosynthetic process →	+0.274	+1.668	<.001	<.001	3	19
OESOPHAGUS	Cholesterol biosynthetic process via desmosterol →	+0.246	+2.458	<.001	<.001	3	19
BONE	Cholesterol biosynthetic process via lathosterol →	+0.216	+0.957	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,551 associations by consensus.

Zymosterol metabolic process by DHCR24 expression — BONE

Explore this box plot interactively →