DGKQ

Across TCGA patient cohorts, DGKQ RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible DGKQ-associated GO terms across cancer lineages are Progesterone biosynthetic process, Regulation of autophagy of mitochondrion, and Negative regulation of peptidyl-threonine phosphorylation. Each is linked with DGKQ in more than 27 cancer types. Because this analysis shows association rather than direction, both DGKQ-to-partner and partner-to-DGKQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Progesterone biosynthetic process grouped by DGKQ-low versus DGKQ-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKQ→partner) and Y-score (partner→DGKQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Progesterone biosynthetic process →	+0.092	+0.681	<.001	<.001	3	28
SCLC	Regulation of autophagy of mitochondrion →	+0.080	+0.711	<.001	<.001	3	26
TGCT	Negative regulation of peptidyl-threonine phosphorylation →	+0.066	+0.514	<.001	<.001	3	25
SCLC	Heparan sulfate proteoglycan catabolic process →	+0.172	+0.880	<.001	<.001	3	24
SCLC	Endocytic recycling →	+0.079	+0.916	<.001	<.001	3	23
OV	Lipophagy →	+0.080	+0.830	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Progesterone biosynthetic process by DGKQ expression — LAML

Explore this box plot interactively →