DGKQ

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DGKQ protein abundance is significantly associated with the RNA expression of many other genes, with 11,830 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DGKQ-associated genes across cancer lineages are DHRS7, OIP5, and RAD51AP1. Each is linked with DGKQ in more than 4 cancer types. Because this analysis shows association rather than direction, both DGKQ-to-partner and partner-to-DGKQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKQ versus DHRS7 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKQ→partner) and Y-score (partner→DGKQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDHRS7 →+0.577+0.444.003.00235
BRCAOIP5 →-0.615-0.283<.001<.00134
BRCARAD51AP1 →-1.125-0.334<.001<.00134
GBMFGF1 →+0.821+0.286.005<.00134
BRCACENPA →-1.198-0.284<.001<.00134
BRCACDC20 →-1.382-0.335<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,830 associations by consensus.

DGKQ vs DHRS7 — OV

Per-sample scatter of DGKQ vs DHRS7 in OV (Pearson r = 0.46).

Explore this scatter interactively →

Exploration