DGKA

Across TCGA patient cohorts, DGKA protein abundance is significantly associated with the protein abundance of many other proteins, with 21,037 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKA-associated proteins across cancer lineages are CSK, SH3BGRL3, and LPXN. Each is linked with DGKA in more than 8 cancer types. Because this analysis shows association rather than direction, both DGKA-to-partner and partner-to-DGKA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKA versus CSK in OV, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKA→partner) and Y-score (partner→DGKA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSK →	+0.265	+0.338	<.001	<.001	3	9
BRCA	SH3BGRL3 →	+0.402	+0.578	<.001	<.001	3	8
GBM	LPXN →	+0.593	+0.322	<.001	<.001	3	8
PDAC	LSP1_S252 →	+0.860	+0.304	<.001	<.001	3	8
GBM	OSTF1 →	+0.412	+0.292	<.001	<.001	3	8
GBM	ARPC1B →	+0.561	+0.271	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,037 associations by consensus.

DGKA vs CSK — OV

Explore this scatter interactively →