DEPDC4

Across TCGA patient cohorts, DEPDC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,668 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DEPDC4-associated proteins across cancer lineages are SUPT16H, MCM2_S27, and MCM6. Each is linked with DEPDC4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DEPDC4-to-partner and partner-to-DEPDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC4 versus SUPT16H in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC4→partner) and Y-score (partner→DEPDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SUPT16H →	+0.443	+0.520	<.001	<.001	3	5
LSCC	MCM2_S27 →	+0.579	+0.444	<.001	<.001	3	5
HNSC	MCM6 →	+0.710	+0.553	<.001	<.001	3	5
LSCC	MED24 →	+0.232	+0.498	<.001	<.001	3	5
LSCC	NAT10 →	+0.324	+0.404	<.001	<.001	3	5
LSCC	ORC4 →	+0.389	+0.509	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,668 associations by consensus.

DEPDC4 vs SUPT16H — HNSC

Explore this scatter interactively →