DEPDC1B

Across TCGA patient cohorts, DEPDC1B mutation is significantly associated with the RNA expression of many other genes, with 1,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEPDC1B-associated genes across cancer lineages are LINC00838, MIR3925, and ATP6V1G1P4. Each is linked with DEPDC1B in more than 1 cancer types. Because this analysis shows association rather than direction, both DEPDC1B-to-partner and partner-to-DEPDC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00838 grouped by DEPDC1B-low versus DEPDC1B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC1B→partner) and Y-score (partner→DEPDC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00838 →	+0.025	+4.470	.004	.005	3	2
LUAD	MIR3925 →	+0.399	+4.888	<.001	.005	3	2
UCEC	ATP6V1G1P4 →	+0.222	+1.592	<.001	.002	3	2
COAD	RNU2-72P →	+0.457	+6.251	.002	.001	3	2
COAD	RN7SL635P →	+0.600	+5.080	.005	.008	3	2
COAD	MIR4652 →	+0.948	+5.893	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,747 associations by consensus.

LINC00838 by DEPDC1B expression — SKCM

Explore this box plot interactively →