DENND6A-AS1

Across TCGA patient cohorts, DENND6A-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,318 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DENND6A-AS1-associated proteins across cancer lineages are RNASEH2A, CSTF2T, and EIF3J_S127. Each is linked with DENND6A-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DENND6A-AS1-to-partner and partner-to-DENND6A-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENND6A-AS1 versus RNASEH2A in PDAC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND6A-AS1→partner) and Y-score (partner→DENND6A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RNASEH2A →	+0.240	+0.420	.005	.003	3	3
LUAD	CSTF2T →	+0.311	+0.376	<.001	.003	3	3
HNSC	EIF3J_S127 →	-0.463	-0.766	.001	.001	3	3
GBM	HDGFL3 →	+0.380	+0.495	<.001	<.001	3	3
CCRCC	TLN1 →	+0.145	+0.373	<.001	<.001	3	2
LUAD	TMED4 →	-0.372	-0.476	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,318 associations by consensus.

DENND6A-AS1 vs RNASEH2A — PDAC

Explore this scatter interactively →