DEFT1P2

Q-omics provides the consensus-scored DEFT1P2 profile across patient tissues and cancer cell-line models. DEFT1P2 expression is associated with patient survival in 2 of 34 cancer types, with the highest sampling consensus in LGG. Additionally, DEFT1P2 RNA expression shows 111 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight LGG, and KIRP as cancer lineages where DEFT1P2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes DEFT1P2 survival associations across molecular data types. DEFT1P2 RNA expression shows survival associations in the most cancer types (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFT1P2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	2	LGG (18)	view →

This table ranks reproducible DEFT1P2 RNA expression–survival associations across cancer types. High DEFT1P2 expression shows unfavorable associations in LGG and BRCA. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .013). Together, the overview and detailed table identify LGG as the clearest survival context for DEFT1P2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.224	0.738	.013	18	view →
BRCA	OS	Tertile	All	0.181	0.579	.028	12	view →

Pink = unfavorable, green = favorable. all 2 lineages →

DEFT1P2-LGG (DFS)

Explore this curve interactively →