DEFT1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DEFT1P2 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated DEFT1P2 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher DEFT1P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DEFT1P2 expression acts as an unfavorable survival marker.

LGG and BRCA are the cancer types where DEFT1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LGGDFSTertileAll0.2240.738.01318view →
BRCAOSTertileAll0.1810.579.02812view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DEFT1P2–LGG (DFS)

Kaplan–Meier survival curve for DEFT1P2 RNA-high vs -low samples in LGG.

Open the LGG breakdown →

Exploration