DEFB4B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB4B RNA expression is significantly associated with the protein abundance of many other proteins, with 2,843 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEFB4B-associated proteins across cancer lineages are EVPL_S2025, BPI, and C6orf132. Each is linked with DEFB4B in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB4B-to-partner and partner-to-DEFB4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB4B versus EVPL_S2025 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB4B→partner) and Y-score (partner→DEFB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCEVPL_S2025 →+0.902+1.897<.001<.00133
OVBPI →+0.879+0.515<.001.00432
HNSCC6orf132 →+0.525+2.060<.001<.00132
OVCCDC92_S211 →-0.482-0.475.001<.00132
OVCOPB2_S859 →-0.758-0.429<.001<.00132
HNSCCTTNBP2NL →+0.239+1.282<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,843 associations by consensus.

DEFB4B vs EVPL_S2025 — HNSC

Per-sample scatter of DEFB4B vs EVPL_S2025 in HNSC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration