DEFB4A

Across TCGA patient cohorts, DEFB4A RNA expression is significantly associated with the protein abundance of many other proteins, with 7,441 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DEFB4A-associated proteins across cancer lineages are CRYBG3_S931, PDZK1IP1, and S100A9. Each is linked with DEFB4A in more than 5 cancer types. Because this analysis shows association rather than direction, both DEFB4A-to-partner and partner-to-DEFB4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB4A versus CRYBG3_S931 in BRCA, with a Pearson correlation of 0.17.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB4A→partner) and Y-score (partner→DEFB4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CRYBG3_S931 →	+0.636	+0.114	.002	.007	3	6
LSCC	PDZK1IP1 →	+0.921	+1.948	.005	<.001	3	4
UCEC	S100A9 →	+0.864	+1.008	<.001	.001	3	4
LSCC	S100A9_T113 →	+1.160	+1.520	<.001	<.001	3	4
UCEC	LCN2 →	+1.032	+1.654	<.001	<.001	3	4
UCEC	S100A8 →	+1.345	+1.636	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,441 associations by consensus.

DEFB4A vs CRYBG3_S931 — BRCA

Explore this scatter interactively →