DEFB131D

Across TCGA patient cohorts, DEFB131D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,653 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB131D-associated GO terms across cancer lineages are Response to misfolded protein, Negative regulation of tumor necrosis factor-mediated signaling pathway, and Regulation of triglyceride biosynthetic process. Each is linked with DEFB131D in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB131D-to-partner and partner-to-DEFB131D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to misfolded protein grouped by DEFB131D-low versus DEFB131D-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB131D→partner) and Y-score (partner→DEFB131D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Response to misfolded protein →	+0.181	+0.011	<.001	.007	3	2
STAD	Negative regulation of tumor necrosis factor-mediated signaling pathway →	+0.107	+0.031	<.001	.003	3	2
STAD	Regulation of triglyceride biosynthetic process →	+0.129	+0.065	<.001	.002	3	2
STAD	Schwann cell differentiation →	+0.170	+0.034	<.001	.001	3	2
STAD	rRNA modification →	+0.198	+0.034	<.001	.001	3	2
STAD	Nucleotide-sugar transmembrane transport →	+0.181	+0.063	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Response to misfolded protein by DEFB131D expression — LUSC

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