Q-omics provides the consensus-scored DEFB131D profile across patient tissues and cancer cell-line models. DEFB131D expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in CESC. Additionally, DEFB131D RNA expression shows 4,047 significant gene co-expression associations, with the highest sampling consensus in STAD. Together, these results highlight CESC, and STAD as cancer lineages where DEFB131D shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB131D survival associations across molecular data types. DEFB131D RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB131D data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	CESC (108)	view →

This table ranks reproducible DEFB131D RNA expression–survival associations across cancer types. High DEFB131D expression shows unfavorable associations in CESC, BRCA, KIRC, LUSC and PRAD. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for DEFB131D RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	All	0.146	0.798	<.001	108	view →
BRCA	DFS	Tertile	All	0.347	0.903	<.001	72	view →
KIRC	OS	Tertile	All	0.528	0.813	.007	54	view →
LUSC	DFS	Tertile	II,III,IV	0.129	0.674	<.001	36	view →
PRAD	OS	Tertile	All	0.265	0.884	<.001	12	view →

Pink = unfavorable, green = favorable. all 5 lineages →

DEFB131D-CESC (OS)

Kaplan–Meier survival curve for DEFB131D RNA expression in CESC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB131D in patient tissues and cancer cell lines. In patient samples, DEFB131D shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,047	STAD (3096)	view →
Function (RNA)	3,653	STAD (3642)	view →