DEFB131D

Across TCGA pan-cancer cohorts, DEFB131D RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated DEFB131D data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher DEFB131D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DEFB131D expression acts as an unfavorable survival marker.

CESC, BRCA, and KIRC are the cancer types where DEFB131D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	All	0.146	0.798	<.001	108	view →
BRCA	DFS	Tertile	All	0.347	0.903	<.001	72	view →
KIRC	OS	Tertile	All	0.528	0.813	.007	54	view →
LUSC	DFS	Tertile	II,III,IV	0.129	0.674	<.001	36	view →
PRAD	OS	Tertile	All	0.265	0.884	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DEFB131D–CESC (OS)

Open the CESC breakdown →