DEFB130B

Q-omics provides the consensus-scored DEFB130B profile across patient tissues and cancer cell-line models. DEFB130B expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, DEFB130B RNA expression shows 685 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight ESCA, and DLBC as cancer lineages where DEFB130B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes DEFB130B survival associations across molecular data types. DEFB130B RNA expression shows survival associations in the most cancer types (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB130B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	1	ESCA (99)	view →

This table ranks reproducible DEFB130B RNA expression–survival associations across cancer types. High DEFB130B expression shows unfavorable associations in ESCA. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify ESCA as the clearest survival context for DEFB130B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.164	0.702	.001	99	view →

Pink = unfavorable, green = favorable. all 1 lineages →

DEFB130B-ESCA (OS)

Explore this curve interactively →