DEFB130B

Across TCGA pan-cancer cohorts, DEFB130B RNA is linked to patient survival in 1 of 34 cancer types, making it the most broadly survival-associated DEFB130B data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher DEFB130B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DEFB130B expression acts as an unfavorable survival marker.

ESCA are the cancer types where DEFB130B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.164	0.702	.001	99	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

DEFB130B–ESCA (OS)

Open the ESCA breakdown →